Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of many myeloma. Its synthesis or review is vital for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A critical compound while in the synthesis of imatinib, a drug that targets particular types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the output method and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care 3-triacetate of breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the cure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, that have various applications, such as antiviral Homes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-four to regulate blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication utilized vildagliptin intermediates to deal with sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).